Photo: Getty ImagesCeliac disease sufferersmay soon be able to safely eat gluten, thanks to a new vaccine currently undergoing testing worldwide.The vaccine, calledNexvax2, targets the immune system to stop the inflammation that typically occurs when people with celiac diseaseconsume gluten. It was first tested in 2011, for the initial trial phase, and was found to be safe.The company that produces Nexvax2, the Massachusetts-based ImmusanT,received $40 million in fundingin 2017, allowing them to continue researching the vaccine. The second round of testing will start in Melbourne, before going out to other cities in Australia. ImmusanT hopes to enroll 150 patients from the United States, Australia and New Zealand in the trial.“The vaccine is designed to target the 90 percent of celiac disease patients with the HLA-DQ2 genetic form of disease,” Dr. Jason Tye-Din, the head of celiac research and gastroenterologist at the Royal Melbourne Hospital, where the trial will start,told theSydney Morning Herald. “A successful therapy that can restore normal gluten tolerance would revolutionize celiac disease management.”RELATED VIDEO: Party City Apologizes and Pulls Ad After Offending People with Gluten AllergiesCurrently, there is no treatment for celiac disease — the only option is to cut out gluten entirely. While going gluten-freebecame trendy among health-conscious peoplein the last decade, for celiac disease sufferers the proteinposes a severe riskto their small intestine, and causes diarrhea, abdominal pain and vomiting.Nexvax2 won’t immediately enable people with celiac to eat gluten again — rather, the vaccine will slowly build up an immunity to the proteins in gluten and end the negative side effects.“Through this study we anticipate making new insights that will further our ability to demonstrate specific suppression of the immune response to gluten epitopes and associated effects of celiac disease,”Dr. Ken Truitt, ImmusanT chief medical officer,told BeyondCeliac.org.
Photo: Getty Images
Celiac disease sufferersmay soon be able to safely eat gluten, thanks to a new vaccine currently undergoing testing worldwide.The vaccine, calledNexvax2, targets the immune system to stop the inflammation that typically occurs when people with celiac diseaseconsume gluten. It was first tested in 2011, for the initial trial phase, and was found to be safe.The company that produces Nexvax2, the Massachusetts-based ImmusanT,received $40 million in fundingin 2017, allowing them to continue researching the vaccine. The second round of testing will start in Melbourne, before going out to other cities in Australia. ImmusanT hopes to enroll 150 patients from the United States, Australia and New Zealand in the trial.“The vaccine is designed to target the 90 percent of celiac disease patients with the HLA-DQ2 genetic form of disease,” Dr. Jason Tye-Din, the head of celiac research and gastroenterologist at the Royal Melbourne Hospital, where the trial will start,told theSydney Morning Herald. “A successful therapy that can restore normal gluten tolerance would revolutionize celiac disease management.”RELATED VIDEO: Party City Apologizes and Pulls Ad After Offending People with Gluten AllergiesCurrently, there is no treatment for celiac disease — the only option is to cut out gluten entirely. While going gluten-freebecame trendy among health-conscious peoplein the last decade, for celiac disease sufferers the proteinposes a severe riskto their small intestine, and causes diarrhea, abdominal pain and vomiting.Nexvax2 won’t immediately enable people with celiac to eat gluten again — rather, the vaccine will slowly build up an immunity to the proteins in gluten and end the negative side effects.“Through this study we anticipate making new insights that will further our ability to demonstrate specific suppression of the immune response to gluten epitopes and associated effects of celiac disease,”Dr. Ken Truitt, ImmusanT chief medical officer,told BeyondCeliac.org.
Celiac disease sufferersmay soon be able to safely eat gluten, thanks to a new vaccine currently undergoing testing worldwide.
The vaccine, calledNexvax2, targets the immune system to stop the inflammation that typically occurs when people with celiac diseaseconsume gluten. It was first tested in 2011, for the initial trial phase, and was found to be safe.
The company that produces Nexvax2, the Massachusetts-based ImmusanT,received $40 million in fundingin 2017, allowing them to continue researching the vaccine. The second round of testing will start in Melbourne, before going out to other cities in Australia. ImmusanT hopes to enroll 150 patients from the United States, Australia and New Zealand in the trial.
“The vaccine is designed to target the 90 percent of celiac disease patients with the HLA-DQ2 genetic form of disease,” Dr. Jason Tye-Din, the head of celiac research and gastroenterologist at the Royal Melbourne Hospital, where the trial will start,told theSydney Morning Herald. “A successful therapy that can restore normal gluten tolerance would revolutionize celiac disease management.”
RELATED VIDEO: Party City Apologizes and Pulls Ad After Offending People with Gluten Allergies
Currently, there is no treatment for celiac disease — the only option is to cut out gluten entirely. While going gluten-freebecame trendy among health-conscious peoplein the last decade, for celiac disease sufferers the proteinposes a severe riskto their small intestine, and causes diarrhea, abdominal pain and vomiting.
Nexvax2 won’t immediately enable people with celiac to eat gluten again — rather, the vaccine will slowly build up an immunity to the proteins in gluten and end the negative side effects.
“Through this study we anticipate making new insights that will further our ability to demonstrate specific suppression of the immune response to gluten epitopes and associated effects of celiac disease,”Dr. Ken Truitt, ImmusanT chief medical officer,told BeyondCeliac.org.
source: people.com
